1999: Study on the long-term effects of multi-drug therapy and other treatment on leprosy

Contribution/research:
Study on the long-term effects of multi-drug therapy and other treatment on leprosy

Award:
The Award of Scientific and Technical Progress of MOH, China, The Third Award, 1999

Winners:
Shen J, Li W, Chen X, Yan L, Ye G, Zhang X, Ran S

Address:
National Center for STD and Leprosy Control, Institute of Dermatology, Chinese Academy of Medical Sciences, 12 Jiangwangmiao Road, Nanjing 210042, P. R. China

Introduction:
The long-term effects and patient's acceptance on multi-drug therapy on leprosy have been investigated in a comprehensive way from clinical, bacteriological and social medicine aspects. The results showed that the study with a great number of samples and a long-term investigation period is of great importance to guide the multi-drug therapy in China. The study on leprosy treatment is mainly on experimental activities and clinical effects of home made anti-leprosy drugs such as pefloxacin, ofloxacin and minocycline against leprosy. This study was first done in China by the methods of animal model, clinical medicine, bacteriological and pathological examination. The results showed that the home made drugs mentioned above can be used for treatment of leprosy in some cases intolerable to the other routine anti-leprosy drugs.